INTRODUCTION
Salicin (CAS NO. 138-52-3, C13H18O7) is an alcoholic β-glucoside. Salicin is produced in (and named after) willow (Salix) bark. It is a biosynthetic precursor to salicylaldehyde.
Salicin acts as an anti-inflammatory agent. Salicin is also commonly found in the bark of Populus species, and the leaves of willows and poplars. which was used as an analgesic, anti-inflammatory, and antipyretic. Salicin is transformed to salicylic acid and has an action very similar to that of aspirin. Salicin was the historical origin of aspirin and is chemically related to it. When consumed, the acetalic ether bridge is broken down. The two parts of the molecule, glucose and salicyl alcohol, then are metabolized separately. By oxidizing the alcohol functional group, the aromatic part finally is metabolized to salicylic acid. Salicin tastes bitter like quinine.
APPLICATION
1) A natural ingredient of antimicrobial bactericidal bioactivity.
The White willow Bark Extract ( Cortex salicis extract) is rich in phenolic glycosides and flavones glycosides, which has strong inhibition on Aspergillus niger, Bacillus subtilis, candida albicans, Escherichia coli, Pseudomonas aeruginosa etc. Also has autoxidation activity. So the white willow bark extract is usually used to produce natural food preservatives; in cosmetics, it can Prevent acne, reduce swelling and pain, so it protects skin, Anti – dandruff.
2) The Salicin as a natural “Aspirin”
The Salicin can be converted into salicylic acid; it can treat fever, cold and infection in the field of medicine.
3) The Salicin as a natural feed additive of anti-inflammatory and helping digestion for animal.
CERTIFICATE OF ANALYSIS AND FINGERPRINT CHROMATOGRAPH
Product Name: |
White Willow Bark Extract |
Latin Name: |
Salix alba L. |
Batch Number: |
20141115 |
Used Part: |
Branch |
Batch Quantity: |
50KG |
Analysis Date: |
Nov.25, 2014 |
Manufacture Date: |
Nov.15, 2014 |
Certificate Date: |
Nov.25, 2014 |
ITEM |
SPECIFICATION |
RESULTS |
Description:
Appearance
Odor
Particle size
Extract Solvents |
White fine Powder
Characteristic
100% pass 80 mesh sieve
Ethanol and Water |
Conforms
Conforms
Conforms
Conforms |
Assay:
Salicin |
By HPLC
≥98% |
98.90% |
Physical:
Loss on Drying
Bulk Density |
≤0.5%
45-60g/100ml |
0.31%
Conforms |
Chemical:
Arsenic (As)
Lead (Pb)
Mercury (Hg)
Cadmium (Cd)
Heavy Metals
Pesticide Residue
Solvent Residue |
≤2ppm
≤5ppm
≤1ppm
≤1ppm
≤20ppm
Meet Eur.Ph.7.0
Meet USP34 |
Conforms
Conforms
Conforms
Conforms
Conforms
Conforms
Conforms |
Microbial:
Total Plate Count
Yeast & Mold
E.Coli
Salmonella
Staphylococcus |
≤1000cfu/g Max
≤100cfu/g Max
Negative
Negative
Negative |
Conforms
Conforms
Conforms
Conforms
Conforms |
Conclusion |
Conform to specification. |
Storage |
Store in cool & dry place. Keep away from strong light and heat. |
Shelf life |
2 years when properly stored. |
Salicin from Willow Bark