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Sophora Flavescens Root Extract

Synonyms: Radix Sophorae Flavescentis Extract Sophora Extract, Total Matrines
Appearance: Nigger Brown liquid or Powder, Light Brown paste or Powder, White Fine Powder or Crystalline
Active ingredients: Total Alkaloids (Matrine, Oxymatrine, Sophoridine, Sophoranol, Sophoramine)
Specification: Botanical pesticide Grade
15% Matrine by HPLC 40%, total alkaloids by Titration, Dark brown Liquid
30% Matrine by HPLC 60%, total alkaloids by Titration, Dark brown Liquid
30% Matrine by HPLC 90%, total alkaloids by Titration, Dark brown Paste
Technical grade:: 98% Matrine by HPLC ( Cosmetic Grade and Pharmacy Grade) 98% Oxymatrine by HPLC White crystal powder Solubility: easy to soluble in water, ethanol, chloroform and Toluol, Benzene.
Shelf life 24 months when properly stored.
INQUIRY
INTRODUCTION

It is extracted from the plant "Sophora Flavescens Ait", which medicinally mainly refers to the dried root of Sophora Flavescens Ait. Which is a plant in the family Leguminosae? And it has a few other names, including Sophora Flavescens radix, light yellow sophora root, Flavescent Sophora Root, Root of Light Yellow Sophora, Sophora Flavescens Root, and more. It is produced all over China and harvested during spring and autumn.

Sophora root mainly contains alkaloids, flavonoids, quinones, and triterpenoid saponins. Alkaloids contain Matrine, oxymatrine, sophoridine, sophoranol, sophoramine, etc. Flavonoids contain kushenol, kuraridin, kuraridinol, kurarinol, neokurarinol, norkurarinol, isokurarinone, kurarinone, and more. Triterpenoid saponins include sophoraflavoside Ⅰ, Ⅱ, Ⅲ, Ⅳ, soyasaponin I, and so on. Quinones are kushequinone A and others.

Matrine ( CAS NO. 519-02-8, Formula:C15H24N2O) as an alkaloid possesses strong antitumor activities in vitro and in vivo. Inhibition of cell proliferation and induction of apoptosis are the likely mechanisms responsible for matrine's antitumor activities. Matrine ( CAS NO. 519-02-8, Formula:C15H24N2O) is a component of the traditional Chinese medical herb Sophora flavescens Ait.

Oxymatrine (CAS NO. 16837-52-8, Chemical formula: C15H24N2O2) is one of many quinolizidine alkaloid compounds extracted from the root of Sophora flavescens, a Chinese herb. It is very similar in structure to matrine, which has one less oxygen atom.

The Matrine ( CAS NO. 519-02-8, Formula: C15H24N2O) and Oxymatrine (CAS NO. 16837-52-8, Chemical formula: C15H24N2O2) are two main ingredients; The Oxymatrine is transformed from Matrine.

Matrine ( CAS NO. 519-02-8, Formula:C15H24N2O) and the related compound Oxymatrine (CAS NO. 16837-52-8, Chemical formula: C15H24N2O2) have an antifeedant effect against formosan subterranean termite. Additionally, it acts as a nematicide against the pine wood nematode which causes pine wilt, as well as pathogenic nematodes which target humans.

 

 

APPLICATION

Matrine and Oxymatrine can be used in cosmetics,medicine.

The matrine means total matrines (all alkaloids) extracted from Sophora Flavescens Ait. Matrine is a high efficiency, broad spectrum, less resistance low toxic, low residue, environmentally friendly Botanical pesticide, by direct contact, subsidiary by stomach poison. Once pests touch it, their nervous system is paralyzed immediately, then protein of their bodies will denaturalize, finally they will die of breathlessness. Mainly control all kinds of Dendrolimus punctatus Walker, Euproctis Pseudoconspersa Strand, Pieris rapae etc insects. Matrine has good functions of pesticide, Sterilization and regulating plant growth etc. Matrine has been widely used on vegetables, fruits, tea, tobacco and so on, Matrine has high efficacy against aphid, cabbage worm, army worm, red spider, mite etc. In addition, we should also pay attention to the efficacy of matrine on vegetable downy mildew, anthracnose etc.

It has stomach poisoning and contact killing effects, and is of low toxicity to humans and animals. Its main mechanism of action is that once the insect comes into contact with the agent, it will paralyze the nerve center, which will then solidify the insect's protein, block the insect's pores, and cause the insect to suffocate and die.
It is both an insecticide and a fungicide, and can also promote plant growth. It is effective against a variety of chewing pests, sucking pests and a variety of fungal, bacterial and viral diseases.
Insecticide targets: aphids, rice planthoppers, thrips, whitefly, tea green leafhopper, pear psyllid, sagittal scale, tobacco caterpillar, cabbage caterpillar, cutworm, American white moth, locust, red spider mite, pine wood nematode, Spodoptera litura and pine caterpillars, etc.

Sterilization targets: Tomato and grape gray mold, citrus tree canker (bacterial disease), rice stripe leaf blight, pear tree scab, cucumber and grape downy mildew, cucumber powdery mildew, etc.

CERTIFICATE OF ANALYSIS AND FINGERPRINT CHROMATOGRAPH

 

ITEM SPECIFICATION RESULTS
Description:
Appearance
Odor
Solubility
Nigger Brown Paste
Characteristic
Soluble in water
Conforms

Conforms

Conforms

Assay

Total alkaloids
Matrine

by
≥50%by titration
≥15%by HPLC
53.80%

15.29%

Physical:

Moisture

Specific Gravity
Residue on lgnition

PH

≤25%
1.02-1.2≤3%
6.5-9.5
24.60%

1.02
1.80%

7.0

Chemical:
Heavy Metals (as Pb)
Arsenic   (as  As₂O₃)
Residual Pesticide
≤10 ppm
≤2ppm
Negative
Conforms
ConformsConforms
Microbial:
Total microbacterial Count
Yeast &Mould
E.Coli
Salmonella
≤1000cfu/g
≤100cfu/gNegative
Negative
Conforms

Conforms

Conforms
Conforms

ITEM SPECIFICATION RESULTS
Description

Appearance
Odor
Solubility

Nigger Brown Paste
Characteristic
Soluble in water
Confoms
Confoms
Conforms
Assay
Total alkaloids
Matrine
by
≥60%by titration
≥30%by HPLC
60.40%
30.32%
Physical:
Specific Gravity
PH
6.5-9.5 1.02
9.0
Chemical:
Heavy Metals (as Pb)
Arsenic  (as  As₂O₃)
Residual Pesticide
≤10 ppm
≤2ppm
Negative
Conforms
Conforms
Conforms
Microbial:
Total microbacterial Count
Yeast &Mould
E.Coli
Salmonella
≤1000cfu/g
≤100cfu/gNegative
Negative
Conforms

Confoms
Confoms
Conforms

ITEM SPECIFICATION RESULTS
Description
Appearance
Odor
Solubility
Light Brown solid Paste
Characteristic
Soluble in water
Confoms
Confoms
Conforms
Assay

Total alkaloids
Matrine

by
≥90%by titration
≥30%by HPLC
95.60%
33.20%
Physical:
Moisture
Residue on ignitiorPH
≤10%
≤0.5%
6.5-9.5
4.10%
0.3%
9.5
Chemical:
Heavy Metals (as Pb)
Arsenic  (as  As₂O₃)
Residual Pesticide
≤10 ppm
≤2ppm
Negative
Confoms
Conforms
Conforms
Microbial:
Total microbacterial Count
Yeast &Mould
E.Coli
Salmonella
≤1000cfu/ç
≤100cfu/gNegative
Negative
Conforms
Confoms
ConformsConforms

 

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