Matrine ( CAS NO. 519-02-8, Formula:C15H24N2O) as an alkaloid possesses strong antitumor activities in vitro and in vivo. Inhibition of cell proliferation and induction of apoptosis are the likely mechanisms responsible for matrine's antitumor activities. Matrine ( CAS NO. 519-02-8, Formula:C15H24N2O) is a component of the traditional Chinese medical herb Sophora flavescens Ait.
The Matrine ( CAS NO. 519-02-8, Formula: C15H24N2O) and Oxymatrine (CAS NO. 16837-52-8, Chemical formula: C15H24N2O2) are two main ingredients; The Oxymatrine is transformed from Matrine.
Matrine ( CAS NO. 519-02-8, Formula:C15H24N2O) and the related compound Oxymatrine (CAS NO. 16837-52-8, Chemical formula: C15H24N2O2) have an antifeedant effect against formosan subterranean termite. Additionally, it acts as a nematicide against the pine wood nematode which causes pine wilt, as well as pathogenic nematodes which target humans.