Macleaya Cordata Extract, Sanguinarine

Macleaya cordata, （also called as Pink Plumepoppy and Bocconia Cordata) a traditional Chinese medicine, is composed of a variety of active alkaloids such as sanguinarine and chelerythrine and is usually used as a natural additive in livestock because of its properties, including anti-microbial, anti-fungal, anti-inflammatory, and pesticidal activity.

Macleaya cordata extract is believed to be an effective natural appetiser in swine, bovine, poultry, and even fish nutrition. Macleaya cordata extract is blended from intact aerial parts and a fraction of quaternary benzo[c]phenanthridine alkaloids (QBAs), primarily sanguinarine and chelerythrine, and standardised to 1.5% w/w.

Sanguinarine (Sanguinarine chloride，CAS NO.5578-73-4,Formula: C20H14NO4.Cl) , a quaternary benzo[c] phenanthridine alkaloid, is synthesised from dihydrosanguinarine, via the activities of dihydrobenzophenanthridine oxidase . It has been shown to have beneficial effects. It is antimicrobial, antifungal, adrenolytic, sympatholytic, immunomodulatory, and anti-inflammatory.

Chelerythrine (Chelerythrine chloride, CAS NO. 3895-92-9, Mocular: C21H18NO4CL) is a quaternary benzo[c] phenanthridine alkaloid. According to studies, it mostly exhibits tumour resistant, microbe resistant, and inflammation resistant qualities. Plus, the substance is a powerful disruptor when it comes to PKC (or protein kinase C). As such, the prospective utilisation of Chelerythrine, as a form of inflammation resistance, has been the topic of much debate. Its qualities are linked to its capacity to engage with DNA and proteins. This is an enzyme that plays an important part in the control of signal transduction, cell propagation, and cell variation.

1) Antibacterial, Antifungal, Antiprotozoan Property.

The Sanguinarine (pseudochelerythrine), chelerythrine, protopine as the main alkaloids (suflate salt) extracted from Macleaya Cordata fruit clip have antibacterial, antifungal, antiprotozoan Property. So it has wild application in injection in Pharmacy, liniment in Cosmetics, also as antiplaque agent in toothpaste.

2) Insecticidal activity

The Sanguinarine and it's mainly isoquinoline alkaloids work together to trichomonas vaginalis and nematode, also killing larvicide. It is widely used in drugs for external use in Pharmacy and make Agricultural insecticide to do insect prevention and fungi-proofing before picking period of vegetable and fruits.

Macleaya Cordata Extract  is an extract of the perennial herbaceous plant of the genus Polygonum genus. Its main component is sanguinarine, and it also contains chelerythrine, proopioidine, α-allocryptine and β-allocryptine. Sanguinarine has broad-spectrum insecticidal and bactericidal activity and can effectively control a variety of agricultural pests and diseases. As a botanical pesticide, sanguinarine has the characteristics of good environmental compatibility and broad action spectrum, and can be used as an important means of comprehensive agricultural control. The Macleaya Cordata Extract with sanguinarine as the main component has acaricidal, insecticidal and bactericidal activities. It has high activity as an acaricide, has broad-spectrum insecticidal activity, and is good against some bacteria. inhibitory effect.

3) A world’s leading phytogenic feed ingredient and Veterinary Drug

It improves the feed intake, digestive performance and leads to a positive effect on amino acids balance and protein utilization, it is natural feed ingredient that can be delivered to all livestock, poultry, aquaculture without a withdrawal periods. Efficiency and increase appetite. Broad, nutritional and physiological gut level support during periods of stress, regardless of the cause. Dosage Common SPEC is 1.5% sanguinarine. 30-50g per Ton.