INTRODUCTION
Osthole (CAS NO. 484-12-8, Molecular Formula: C15H16O3) also called as Osthol, is a kind of coumarins in the Fructus Cnidii Extract, which is extracted from the seed (Fructus Cnidii)of the plant “Cnidium monnieri （L.）Cuss.”.
Osthole has functions of Antifungus, Antivirus, anti-inflammatory, anesthetization and Enhancing Immune etc.
APPLICATION
1) Pharmaceutical field to stimulate sexual desire and enhance human immunity.
2) Cosmetic Field to Improve the pathological changes of psoriasis, with strong anti-inflammatory, anti-allergy, antipruritic effect
3) Osthole: A natural ingredient in botanical Pesticides & Bactericide (botanical source) to control diseases and pests:
A) It has inhibitory effect on gibberellum and Rhizoctonia solani of wheat.
B) As for cucumber and cabbage downy mildew, cucumber powdery mildew, apple leaf blight, orthomycosis and other plant pathogens Fungi, The Osthole has a broad spectrum of inhibitory activity.
C) Killing effect on the larval lepidoptera tea geometrid, plutella xylostella, rapeseed, the newly hatched noctuidae, aphid.
CERTIFICATE OF ANALYSIS AND FINGERPRINT CHROMATOGRAPH
| CERTIFICATE OF ANALYSIS |
| Product Name |
Cnidium Fruit Extract |
Botanical Name: |
Cnidium monnieric(L.)Cuss |
| Batch Number: |
20210325 |
Used Part: |
Fruit |
| Batch Quantity: |
150KG |
Analysis Date: |
April 2,2021 |
| Manufacture Date: |
March 25,2021 |
Certificate Date: |
April 2,2021 |
|
| ITEM |
SPECIFICATION |
RESULTS |
| Description
Appearance
Odor&Taste
Particle size
Extract Solvent |
Faint yellow fine Powder
Characteristics
100%pass 80 mesh sieveEthanol &Water |
Conforms
Confoms
ConformsConforms |
Assay
Osthole |
≥90%by HPLC |
90.39% |
Physical:
Loss on Drying
Total Ash |
≤5.0 %
≤5.0 % |
0.52%
0.39% |
Chemical:
Heavy Metals
Arsenic(As
Lead (Pb)
Mercury (Hg
Cadmium (Cd) |
≤10 ppm
≤2ppm
≤5ppm
≤0.1ppm
≤1ppm |
Conforms
Confoms
Confoms
Conforms
Conforms |
Microbial:
Total Plate Count
Yeast &Mold
E.Coli
Salmonella sppStaphylococcus aureus
Pseudomonas aeruginosa |
≤1000cfu/ç
≤100cfu/g
Absent
Absent
Absent
Absent |
Conforms
ConformsConfoms
ConfomsConfoms
Conforms |
| Conclusion Conform to specification. |
| Storage Store in cool &dry place.Keep away from strong light and heat.
Shelf life 24 months when properly stored. |
Chromatogram 90% Osthole
