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Chelerythrine, Chelerythrine Chloride

Synonyms: Chelerythrine Hydrochloride, Chelerythrine Chloride
Appearance: Light Yellow Fine Powder, Bitter
Active ingredients: Isoquinoline alkaloids: Chelerythrine (Chelerythrine chloride)
Specification: 98% Chelerythrine Chloride by HPLC
Shelf life 24 months when properly stored.
INQUIRY
INTRODUCTION

Chelerythrine (Chelerythrine chloride, CAS NO. 3895-92-9, Mocular: C21H18NO4CL) is a quaternary benzo[c] phenanthridine alkaloid. According to studies, it mostly exhibits tumour resistant, microbe resistant, and inflammation resistant qualities. Plus, the substance is a powerful disruptor when it comes to PKC (or protein kinase C). As such, the prospective utilisation of Chelerythrine, as a form of inflammation resistance, has been the topic of much debate. Its qualities are linked to its capacity to engage with DNA and proteins. This is an enzyme that plays an important part in the control of signal transduction, cell propagation, and cell variation.

APPLICATION

Feed, Pharmacy, Cosmetics, Etc.

CERTIFICATE OF ANALYSIS AND FINGERPRINT CHROMATOGRAPH

 

Product Name:

Macleaya Cordata Extract

Latin Name:

Macleayae Cordatae

Batch Number:

20200202 (recrystallization)

Used Part:

Fruit

Batch Quantity:

60Gram

Analysis Date:

February 20, 2020

Manufacture Date:

Dec 1, 2019

Certificate Date:

February 20, 2020

ITEM

SPECIFICATION

RESULTS

Description:

Appearance

Odor

Orange Yellow fine Powder

Irritation and Bitterness

Conforms

Conforms

Assay:

Chelerythrine Chloride

by HPLC

98% (on Dry Base)

98.60%

Physical:

Loss on Drying

Total Ash

5%

1%

4.70%

Conforms

Conclusion

Conform to specification.

Storage

Store in cool & dry place. Keep away from strong light and heat.

Shelf life

2 years when properly stored.

CERTIFICATE OF ANALYSIS

Product Name:

Macleaya Cordata Extract

Latin Name:

Macleayae Cordatae

Batch Number:

20200518

Used Part:

Fruit

Batch Quantity:

260Grams

Analysis Date:

May 18, 2020

Manufacture Date:

May 18, 2020

Certificate Date:

May 18, 2020

ITEM

SPECIFICATION

RESULTS

Description:

Appearance

Odor

Yellow fine Powder

Irritation and Bitterness

Conforms

Conforms

Assay:

Chelerythrine Chloride

Sanguinarine Chloride

by HPLC

98% (On Dry Base)

1% (On Dry Base)

98.20%

0.58%

Physical:

Loss on Drying

Total Ash

5%

1%

1.56%

Conforms

Chemical:

Arsenic (As)

Lead (Pb)

Cadmium (Cd)

Mercury (Hg)

Heavy Metals  

2ppm

5ppm

1ppm

0.1ppm

10ppm

Conforms

Conforms

Conforms

Conforms

Conforms

Microbial:

Total Plate Count  

Yeast & Mold

E.Coli

Salmonella

1000cfu/g Max

100cfu/g Max

Negative

Negative

Conforms

Conforms

Conforms

Conforms

Conclusion

Conform to specification.

Storage

Store in cool & dry place. Keep away from strong light and heat.

Shelf life

2 years when properly stored.

Chelerythrine HPLC chromatogram 20200518 Purity Chelerythrine HPLC chromatogram 20200202

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